MathWorks - Mobile View
  • Sign In to Your MathWorks AccountSign In to Your MathWorks Account
  • Access your MathWorks Account
    • My Account
    • My Community Profile
    • Link License
    • Sign Out
  • Products
  • Solutions
  • Academia
  • Support
  • Community
  • Events
  • Get MATLAB
MathWorks
  • Products
  • Solutions
  • Academia
  • Support
  • Community
  • Events
  • Get MATLAB
  • Sign In to Your MathWorks AccountSign In to Your MathWorks Account
  • Access your MathWorks Account
    • My Account
    • My Community Profile
    • Link License
    • Sign Out

Videos and Webinars

  • MathWorks
  • Videos
  • Videos Home
  • Search
  • Videos Home
  • Search
  • Contact sales
  • Trial software
  Register to watch video
  • Description
  • Related Resources

The Particular Nature of Molecular Information in Engineered Biochemical Communication Systems

From the series: MathWorks Research Summit

Prof. Massimiliano Pierobon, Department of Computer Science and Engineering, University of Nebraska-Lincoln

Define and characterize information flow in communication systems based on molecule exchange and biochemical reactions, with the help of simulations realized through SimBiology®. The Molecular and Biochemical Telecommunications (MBiTe) Lab at the University of Nebraska-Lincoln, led by Dr. Massimiliano Pierobon, investigates communication systems based on the encoding, propagation, and decoding of information through biochemical reactions and molecule exchange. The definition of these systems ranges from molecule diffusion to the complex information flow at the basis of biological cells’ activity and multicellular organisms’ homeostasis. The biocompatibility and nanoscale feasibility make molecular communication a promising paradigm for engineering the interconnections between embedded computing systems able to not only interact with biological processes but also use these same processes as their building blocks, i.e., the Internet of Bio-Nano Things. The latter, enabled by emerging tools from synthetic biology for the genetic programming of biological cells’ behavior, opens novel application scenarios for communication and information theory, ranging from health care to environmental protection, defense, and consumer industries, towards the rational forward engineering of bio-sensing, stimulation, or actuation of biochemical processes, or even augmentation of the functionalities of the human body.

  • Review the features of molecular communication theory as a paradigm, and its scope within the research in communication systems engineering.
  • Survey the types of communication systems that have been realized through synthetic biology.
  • Characterize a molecular communication system based on engineered cells with the development of an information theoretical framework to quantify biochemical information flow. 
  • Use SimBiology to simulate these engineered biochemical systems, and evaluate performance based on the results.
  • Devise a novel methodology to engineer these systems with the synthetic biology formalism of biological circuits.  This methodology is inspired by recent studies favoring the efficiency of analog computation over digital in biological cells, and it resulted in an award at the IEEE INFOCOM conference.
  • By stemming from this methodology, review the design of a parity-check coding scheme implemented entirely in the biochemical domain, through activation and repression of genes, and biochemical reactions, rather than classical electrical circuits.
  • Compare analytical formulations of information flow within this engineered coding scheme with simulation results based on SimBiology.

This talk concludes with the impact this research and the use of SimBiology had on the success of our international Genetically Engineered Machines (iGEM) team of undergraduate students.

This work was supported by the U.S. National Science Foundation under Grant CISE CCF-1816969.

Related Products

  • MATLAB
  • SimBiology

Feedback

Featured Product

MATLAB

  • Request Trial
  • Get Pricing

Up Next:

Use the HEBI Robotics API for MATLAB and execute robot control algorithms in real-time directly from MATLAB scripts.
8:56
Achieving Real-Time Robotics Control with MATLAB
View full series (17 Videos)

Related Videos:

29:45
CAN Communication with Your ECUs and the Vehicle Network...
32:16
Dynamic Modelling and Simulation to Design, Integrate, and...
17:46
Systems Engineering Requires a Paradigm Shift
1:10
Unique Systems require Unique Forecast Models
53:52
Developing Measurement and Analysis Systems Using MATLAB

View more related videos

MathWorks - Domain Selector

Select a Web Site

Choose a web site to get translated content where available and see local events and offers. Based on your location, we recommend that you select: .

Select web site

You can also select a web site from the following list:

How to Get Best Site Performance

Select the China site (in Chinese or English) for best site performance. Other MathWorks country sites are not optimized for visits from your location.

Americas

  • América Latina (Español)
  • Canada (English)
  • United States (English)

Europe

  • Belgium (English)
  • Denmark (English)
  • Deutschland (Deutsch)
  • España (Español)
  • Finland (English)
  • France (Français)
  • Ireland (English)
  • Italia (Italiano)
  • Luxembourg (English)
  • Netherlands (English)
  • Norway (English)
  • Österreich (Deutsch)
  • Portugal (English)
  • Sweden (English)
  • Switzerland
    • Deutsch
    • English
    • Français
  • United Kingdom (English)

Asia Pacific

  • Australia (English)
  • India (English)
  • New Zealand (English)
  • 中国
    • 简体中文Chinese
    • English
  • 日本Japanese (日本語)
  • 한국Korean (한국어)

Contact your local office

  • Contact sales
  • Trial software

Explore Products

  • MATLAB
  • Simulink
  • Student Software
  • Hardware Support
  • File Exchange

Try or Buy

  • Downloads
  • Trial Software
  • Contact Sales
  • Pricing and Licensing
  • How to Buy

Learn to Use

  • Documentation
  • Tutorials
  • Examples
  • Videos and Webinars
  • Training

Get Support

  • Installation Help
  • Answers
  • Consulting
  • License Center
  • Contact Support

About MathWorks

  • Careers
  • Newsroom
  • Social Mission
  • Contact Sales
  • About MathWorks

MathWorks

Accelerating the pace of engineering and science

MathWorks is the leading developer of mathematical computing software for engineers and scientists.

Discover…

  • Select a Web Site United States
  • Patents
  • Trademarks
  • Privacy Policy
  • Preventing Piracy
  • Application Status

© 1994-2021 The MathWorks, Inc.

  • Facebook
  • Twitter
  • Instagram
  • YouTube
  • LinkedIn
  • RSS

Join the conversation