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Last seen: 6 maanden ago | Active since 2023

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integration tolerance has not met
Hi I encountered an issue in implementing the growth rate of the tumor. In the following equation, both tumor carrying capacity...

6 maanden ago | 1 answer | 0

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answer

Question

Changing the result of a simulation with changing the units
Hi, If the injected amount in model compartments is in mole and the transfer rates are in 1/hour. I set the domensional analys...

ongeveer een jaar ago | 1 answer | 0

1

answer

Question

How to find the sensitivity of the model output if it is a variable for repeated assignment?
Hi, I want to find the sensitivity of model output which is a tissue mass for models parameters. I received an red flag that ...

ongeveer een jaar ago | 2 answers | 0

2

answers

Question

how to handle the error 'Levenberg-Marquardt algorithm the Jacobian at BETA0 is ill-conditioned'?
Hi, I try to run the fit in Simbiology using 'mixed effects' modeling. The transformation is exp(theta1+eta1). The 'error model...

ongeveer een jaar ago | 1 answer | 0

1

answer

Question

Why are population estimated parameters values the same as individual estimated parameters values?
Hi, I good patients data. I did population fit 'mixed effect'. The fits for individual patients were very good but the populati...

ongeveer een jaar ago | 1 answer | 0

1

answer

Question

Investigating the effect of two covariates to an estimated parameter
Hi, I have data for different patients and I want to investigate the effect of two covariates to an estimated parameter while...

ongeveer een jaar ago | 1 answer | 0

1

answer

Question

changes the the simulated mass with changing the absolute and relative tolerance
Hi, The mass of the tissue under the effect of a drug goes to very small values, i.e. in the order 10^-12, which is unrealistic...

meer dan een jaar ago | 1 answer | 0

1

answer

Question

species go to negative values
Hi I developed a model in Simbiology simulating the effect of a drug on a tissue mass. Sometime, I received a message that the...

meer dan een jaar ago | 2 answers | 0

2

answers

Question

different event functions for the same species
Hi, I developed a model in Simbiology in which Fw is a parameter as a function of mass. The mass varies with time. I wa...

meer dan een jaar ago | 1 answer | 0

1

answer

Question

A variable is specified by more than one assignment rule
Hi, I have a species A_Total = a + b + c, where a, b and c are other species in the same compartment. I have to set a boundary...

meer dan een jaar ago | 1 answer | 0

1

answer

Question

Lognormal distribution parameters mu and sigma
Hi, I want to generate a lognormal distribution for a set of data measurments using Simbiology model analyzer. I need to inser...

meer dan een jaar ago | 3 answers | 0

3

answers

Question

Extracting Histogram data for plot generation
Hi, I generated a sample of lognormal distribution using Simbiology analyzer. I want to extract the data of the samples' hist...

meer dan een jaar ago | 2 answers | 0

2

answers

Question

Dimensional analysis issue because of the function 'log' in the rule
Hi! When I run a simulation in my model developed in Simbiolog, I received the following warning message: "Unable to perform d...

meer dan een jaar ago | 1 answer | 0

1

answer

Question

Sensitivity analysis in Simbiology
Hi, I want to perform sensitivity analysis for my Simbiology model. I have encountered the following error. Would you please ex...

bijna 2 jaar ago | 1 answer | 0

1

answer

Question

Change in simulation output with changing in the units of stop time
Hi, I defined units for all parameters in my Smbiology model and the model runs simulations. The unit of time for all paramet...

ongeveer 2 jaar ago | 1 answer | 0

1

answer

Question

Failure of dimensional analysis for a rule
Hi, I have a rule y=x^0.35. x has the dimension of mass. An error message showed up saying that the exponent must be an integer...

ongeveer 2 jaar ago | 2 answers | 1

2

answers

Question

Dimension of the species
Hi, In my model in Simbiology, it has a species with dimension of (molecules/time) and connected with a release rate reaction. ...

ongeveer 2 jaar ago | 1 answer | 0

1

answer

Question

Adding erf(x) to a rule in Simbiology
Hello, I have a rule in my model Y(x) = x, for example, in Simbiology app. I want o add the erf(x) for Y(x) to run a simulati...

meer dan 2 jaar ago | 1 answer | 0

1

answer

Question

Simulation error in Simbiology
Hi, I checked the tumor growth model in the library of Simbiology. I noticed if I increase the drug concentration to very high ...

meer dan 2 jaar ago | 1 answer | 0

1

answer

Question

Error message regarding CVODES
Hi, While I was running a simulation in a model I developed in Simbiology, I recieved the following error: CVODES returned -...

meer dan 2 jaar ago | 0 answers | 0

0

answers

Question

Unites of the transfer rates
Hi, The simulations of my model differ at different unites of transfer rates. For example, the following are plots for the same...

meer dan 2 jaar ago | 1 answer | 0

1

answer

Question

Adding equations as a function of time
Hi, Could you please help me in solving the following: I set a trigger event in Simbiology that when 'X' species exceeds a cer...

meer dan 2 jaar ago | 1 answer | 0

1

answer

Question

The fluctuation of the content of a species between negative and positive
The model I am developing in Simbiology includes a drug species in which large repeated amounts of doses are injected. It has no...

meer dan 2 jaar ago | 1 answer | 0

1

answer

Question

What does a dashed line in simbiology mean?
I found a reaction connecting between two species_1 and species_2 in a simbiology model. There is a dashed line connecting betwe...

meer dan 2 jaar ago | 2 answers | 0

2

answers

Question

Adding and configuring events
In simbiology, there is an event trigger that configure events at a SPECIFIC TIME. In my model, the content of m species is numb...

meer dan 2 jaar ago | 1 answer | 0

1

answer

Question

How to assign a transfer rate which changes with time in Simbiology?
I need to connect between two species in Simbiology. The transfer rate (k) in the reaction is an equation which depends on time ...

bijna 3 jaar ago | 1 answer | 0

1

answer