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Automating Parameter Identifiability Analysis in SimBiology
Is it possible to develop a MATLAB Live Script that automates a series of SimBiology model fits to obtain likelihood profiles? The goal is to fit a kinetic model to experimental data while systematically fixing the value of one kinetic constant (e.g., k1) and leaving the others unrestricted.
The script would perform the following:
Use a pre-configured SimBiology project where the best fit to the experimental data has already been established (including dependent/independent variables, covariates, the error model, and optimization settings).
Iterate over a defined sequence of fixed values for a chosen parameter.
For each fixed value, run the estimation to optimize the remaining parameters.
Record the resulting Sum of Squared Errors (SSE) for each run.
The final output would be a likelihood profile—a plot of SSE versus the fixed parameter value (e.g., k1)—to assess the practical identifiability of each model parameter.
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For some time now, this has been bugging me - so I thought to gather some more feedback/information/opinions on this.
What would you classify Recursion? As a loop or as a vectorized section of code?
For context, this query occured to me while creating Cody problems involving strict (so to speak) vectorization - (Everyone is more than welcome to check my recent Cody questions).
To make problems interesting and/or difficult, I (and other posters) ban functions and functionalities - such as for loops, while loops, if-else statements, arrayfun() and the rest of the fun() family functions. However, some of the solutions including the reference solution I came up with for my latest problem, contained recursion.
I am rather divided on how to categorize it. What do you think?
I came across this fun video from @Christoper Lum, and I have to admit—his MathWorks swag collection is pretty impressive! He’s got pieces I even don’t have.
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- Which one is your favorite?
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Show off your swag and share it with the community! 🚀
I saw this YouTube short on my feed: What is MATLab?
I was mostly mesmerized by the minecraft gameplay going on in the background.
Found it funny, thought i'd share.
Trinity
- It's the question that drives us, Neo. It's the question that brought you here. You know the question, just as I did.
Neo
- What is the Matlab?
Morpheus
- Unfortunately, no one can be told what the Matlab is. You have to see it for yourself.
And also later :
Morpheus
- The Matlab is everywhere. It is all around us. Even now, in this very room. You can feel it when you go to work [...]
The Architect
- The first Matlab I designed was quite naturally perfect. It was a work of art. Flawless. Sublime.
[My Matlab quotes version of the movie (Matrix, 1999) ]
Hi,
I have some problem, I want to upload my data that sample rate at 500HZ, every sevral seconds.
My data include 12 bytes, and it measure 500HZ, for example for 15 seconds I coolect 15*500*12 = 84KB.
Can I upload this data to ThingSpeak? It is possible to use with Free acount (I am student and this is my project)
How can help me..
I designed and stitched this last week! It uses a total of 20 DMC thread colors, and I frequently stitched with two colors at once to create the gradient.
Hey cody fellows :-) !
I recently created two problem groups, but as you can see I struggle to set their cover images :
What is weird given :
- I already did it successfully twice in the past for my previous groups ;
- If you take one problem specifically, Problem 60984. Mesh the icosahedron for instance, you can normally see the icon of the cover image in the top right hand corner, can't you ?
- I always manage to set cover images to my contributions (mostly in the filexchange).
I already tried several image formats, included .png 4/3 ratio, but still the cover images don't set.
Could you please help me to correctly set my cover images ?
Thank you.
Nicolas
Resharing a fun short video explaining what MATLAB is. :)
Is there a hardware support package available for the MP series?
I'm facing an issue where my Thinkspeak graph is not displaying, even though I'm using exactly the same code as my friend. The code works perfectly in their Thinkspeak account, but not on mine. I've checked the API keys, channel settings, and data formats, but everything seems similar. Has anyone else faced this problem, or do you have tips on what to check next? Suggestions are welcome!
