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Hey Cool Coders! 😎
Let’s get to know each other. Drop a quick intro below and meet your teammates! This is your chance to meet teammates, find coding buddies, and build connections that make the contest more fun and rewarding!
You can share:
- Your name or nickname
- Where you’re from
- Your favorite coding topic or language
- What you’re most excited about in the contest
Let’s make Team Cool Coders an awesome community—jump in and say hi! 🚀
Welcome to the Cody Contest 2025 and the Cool Coders team channel! 🎉
You stay calm under pressure. No panic, no chaos—just smooth problem-solving. This is your space to connect with like-minded coders, share insights, and help your team win. To make sure everyone has a great experience, please keep these tips in mind:
- Follow the Community Guidelines: Take a moment to review our community standards. Posts that don’t follow these guidelines may be flagged by moderators or community members.
- Ask Questions About Cody Problems: When asking for help, show your work! Include your code, error messages, and any details needed to reproduce your results. This helps others provide useful, targeted answers.
- Share Tips & Tricks: Knowledge sharing is key to success. When posting tips or solutions, explain how and why your approach works so others can learn your problem-solving methods.
- Provide Feedback: We value your feedback! Use this channel to report issues or share creative ideas to make the contest even better.
Have fun and enjoy the challenge! We hope you’ll learn new MATLAB skills, make great connections, and win amazing prizes! 🚀
Automating Parameter Identifiability Analysis in SimBiology
Is it possible to develop a MATLAB Live Script that automates a series of SimBiology model fits to obtain likelihood profiles? The goal is to fit a kinetic model to experimental data while systematically fixing the value of one kinetic constant (e.g., k1) and leaving the others unrestricted.
The script would perform the following:
Use a pre-configured SimBiology project where the best fit to the experimental data has already been established (including dependent/independent variables, covariates, the error model, and optimization settings).
Iterate over a defined sequence of fixed values for a chosen parameter.
For each fixed value, run the estimation to optimize the remaining parameters.
Record the resulting Sum of Squared Errors (SSE) for each run.
The final output would be a likelihood profile—a plot of SSE versus the fixed parameter value (e.g., k1)—to assess the practical identifiability of each model parameter.
I want to observe the time (Tmax) to reach maximum drug concentration (Cmax) in my model. I have set up the OBSERVABLES as follows (figure1): Cmax = max(Blood.lL15); Tmax_LT = time(Conc_lL15_LT_nm == max(Conc_lL15_LT_nm)); Tmax_Tm = time(Conc_lL15_Tumor_nm == max(Conc_lL15_Tumor_nm)); After running the Sobol indices program for global sensitivity analysis, with inputs being some parameters and their ranges, the output for Cmax works, but there are some prompts, as shown in figure2. Additionally, when outputting Tmax, the program does not run successfully and reports some errors, as shown in figure2. How can I resolve the errors when outputting Tmax?
We are thrilled to announce the grand prize winners of our MATLAB Shorts Mini Hack contest! This year, we invited the MATLAB Graphics and Charting team, the authors of the MATLAB functions used in every entry, to be our judges. After careful consideration, they have selected the top three winners:
Judge comments: Realism & detailed comments; wowed us with Manta Ray
2nd place – Jenny Bosten
Judge comments: Topical hacks : Auroras & Wind turbine; beautiful landscapes & nightscapes
3rd place - Vasilis Bellos
Judge comments: Nice algorithms & extra comments; can’t go wrong with Pumpkins
Judge comments: Impressive spring & cubes!
In addition, after validating the votes, we are pleased to announce the top 10 participants on the leaderboard:
Congratulations to all! Your creativity and skills have inspired many of us to explore and learn new skills, and make this contest a big success!
Dear MATLAB contest enthusiasts,
Welcome to the third installment of our interview series with top contest participants! This time we had the pleasure of talking to our all-time rock star – @Jenny Bosten. Every one of her entries is a masterpiece, demonstrating a deep understanding of the relationship between mathematics and aesthetics. Even Cleve Moler, the original author of MATLAB, is impressed and wrote in his blog: "Her code for Time Lapse of Lake View to the West shows she is also a wizard of coordinate systems and color maps."
you to read it to learn more about Jenny’s journey, her creative process, and her favorite entries.
Question: Who would you like to see featured in our next interview? Let us know your thoughts in the comments!
Over the past 4 weeks, 250+ creative short movies have been crafted. We had a lot of fun and, more importantly, learned new skills from each other! Now it’s time to announce week 4 winners.
Nature:
3D:
Seamless loop:
Holiday:
Fractal:
Congratulations! Each of you won your choice of a T-shirt, a hat, or a coffee mug. We will contact you after the contest ends.
Weekly Special Prizes
Thank you for sharing your tips & tricks with the community. These great technical articles will benefit community users for many years. You won a limited-edition pair of MATLAB Shorts!
In week 5, let’s take a moment to sit back, explore all of the interesting entries, and cast your votes. Reflect what you have learned or which entries you like most. Share anything in our Discussions area! There is still time to win our limited-edition MATLAB Shorts.
We are thrilled to see the incredible short movies created during Week 3. The bar has been set exceptionally high! This week, we invited our Community Advisory Board (CAB) members to select winners. Here are their picks:
Mini Hack Winners - Week 3
Game:
Holidays:
Fractals:
Realism:
Great Remixes:
Seamless loop:
Fun:
Weekly Special Prizes
Thank you for sharing your tips & tricks with the community. You won a limited-edition MATLAB Shorts.
We still have plenty of MATLAB Shorts available, so be sure to create your posts before the contest ends. Don't miss out on the opportunity to showcase your creativity!
Just in two weeks, we already have 150+ entries! We are so impressed by your creative styles, artistic talents, and ingenious programming techniques.
Now, it’s time to announce the weekly winners!
Mini Hack Winners - Week 2
Seamless loop:
Nature & Animals:
Game:
Synchrony:
Remix of previous Mini Hack entries
Movie:
Congratulations to all winners! Each of you won your choice of a T-shirt, a hat, or a coffee mug. We will contact you after the contest ends.
In week 3, we’d love to see and award entries in the ‘holiday’ category.
Weekly Special Prizes
Thank you for sharing your tips & tricks with the community. You won limited-edition MATLAB Shorts.
We highly encourage everyone to share various types of content, such as tips and tricks for creating animations, background stories of your entry, or learnings you've gained from the contest.
There are so many incredible entries created in week 1. Now, it’s time to announce the weekly winners in various categories!
Nature & Space:
Seamless Loop:
Abstract:
Remix of previous Mini Hack entries:
Early Discovery
Holiday:
Congratulations to all winners! Each of you won your choice of a T-shirt, a hat, or a coffee mug. We will contact you after the contest ends.
In week 2, we’d love to see and award more entries in the ‘Seamless Loop’ category. We can't wait to see your creativity shine!
Tips for Week 2:
1.Use AI for assistance
The code from the Mini Hack entries can be challenging, even for experienced MATLAB users. Utilize AI tools for MATLAB to help you understand the code and modify the code. Here is an example of a remix assisted by AI. @Hans Scharler used MATLAB GPT to get an explanation of the code and then prompted it to ‘change the background to a starry night with the moon.’
2. Share your thoughts
Share your tips & tricks, experience of using AI, or learnings with the community. Post your knowledge in the Discussions' general channel (be sure to add the tag 'contest2024') to earn opportunities to win the coveted MATLAB Shorts.
3. Ensure Thumbnails Are Displayed:
You might have noticed that some entries on the leaderboard lack a thumbnail image. To fix this, ensure you include ‘drawframe(1)’ in your code.
Over the past week, we have seen many creative and compelling short movies! Now, let the voting begin! Cast your votes for the short movies you love. Authors, share your creations with friends, classmates, and colleagues. Let's showcase the beauty of mathematics to the world!
We know that one of the key goals for joining the Mini Hack contest is to LEARN! To celebrate knowledge sharing, we have special prizes—limited-edition MATLAB Shorts—up for grabs!
These exclusive prizes can only be earned through the MATLAB Shorts Mini Hack contest. Interested? Share your knowledge in the Discussions' general channel (be sure to add the tag 'contest2024') to earn opportunities to win the coveted MATLAB Shorts. You can share various types of content, such as tips and tricks for creating animations, background stories of your entry, or learnings you've gained from the contest. We will select different types of winners each week.
We also have an exciting feature announcement: you can now experiment with code in MATLAB Online. Simply click the 'Open in MATLAB Online' button above the movie preview section. Even better! ‘Open in MATLAB Online’ is also available in previous Mini Hack contests!
We look forward to seeing more amazing short movies in Week 2!
We're excited to announce that the 2024 Community Contest—MATLAB Shorts Mini Hack starts today! The contest will run for 5 weeks, from Oct. 7th to Nov. 10th.
What creative short movies will you create? Let the party begin, and we look forward to seeing you all in the contest!
Dear contest participants,
The 2024 Community Contest—MATLAB Shorts Mini Hack—is just one week away! Last year, we challenged you to create a 48-frame, 2-second animation. This year, we're doubling the fun by increasing the frame count to 96 and adding audio support. Your mission? Create a short movie!
As always, whether you are a seasoned MATLAB user or just a beginner, you can participate in the contest and have opportunities to win amazing prizes.
Timeframe:
- The contest will run for 5 weeks, from Oct. 7th to Nov. 10th, Eastern Time.
General Rules:
- The first week is dedicated to entry creation, and the fifth week is reserved for voting only.
- Create a 96-frame, 4-second animation and add audio. We will loop it 3 times to create a 12-second short movie for you.
- The character limit remains at 2,000 characters.
Prizes
- You will have opportunities to win compelling prizes, including Amazon gift cards, MathWorks T-shirts, and virtual badges. We will give out both weekly prizes and grand prizes.
Warm-up!
With one week left before the contest begins, we recommend you warm up by reading a fantastic article: Walkthrough: making Little Nemo's airship in MATLAB by @Tim. The article shares both technical insights and the challenges encountered along the way.
The MATLAB Central Community Team
Dear MATLAB contest enthusiasts,
In the 2023 MATLAB Mini Hack Contest, Tim Marston captivated everyone with his incredible animations, showcasing both creativity and skill, ultimately earning him the 1st prize.
We had the pleasure of interviewing Tim to delve into his inspiring story. You can read the full interview on MathWorks Blogs: Community Q&A – Tim Marston.
Last question: Are you ready for this year’s Mini Hack contest?
Hi All,
I'm currently verifying a global sensitivity analysis done in SimBiology and I'm a touch confused. This analysis was run with every parameter and compartment volume in the model. To my understanding the fraction of unexplained variance is 1 - the sum of the first order variances, therefore if the model dynamics are dominated by interparameter effects you might see a higher fraction of unexplained variance. In this analysis however, as the attached figure shows (with input at t=20 minutes), the most sensitive four parameters seem to sum, in first order sensitivities to roughly one at each time point and the total order sensitivies appear nearly identical. So how is the fraction of unexplained variance near one?
Thank you for your help!
Hi to everyone!
To simplify the explanation and the problem, I simulated the kinetics of an irreversible first-order reaction, A -> B. I implemented it in two independent compartments, R and P. I simulated the effect of a dilution in R by doubling at t= 0,1 the R volume. I programmed in P that, at t = 0.1, the instantaneous concentration of A and B would be reduced by half. I am sending an attach with the implementation of these simulations in the Simbiology interface.
When the simulations of the two compartments are plotted, it can be seen that the responses are not equal. That is, from t = 0.1 s, the reaction follow an exponential function in R with half of the initial amplitude and half of the initial value of k1. That is, the relaxation time is doubled. Meanwhile, in P, from t = 0.1, the reaction follows exponential kinetics with half the amplitude value but maintaining the initial value of k = 10. Without a doubt, the correct simulation is the latter (compartment P) where only the effect is observed in the amplitude and not in the relaxation time. Could you tell me what the error is that makes these kinetics that should be equal not be?
Thank you in advance!
Luis B.
Hi All,
I've been producing a QSP model of glucose homeostasis for a while now for my PhD project, recently I've been able to expand it to larger time series, i.e. 2 days of data rather than a singular injection or a singular meal. My problem is as follows: If I put 75g of glucose into my stomach glucose species any later than (exactly) 8.5 hours I get an integration tolerance error. Curiosly, I can put 25g of glucose in at any time up to 15.9 hours, then any later an error. I have disabled all connections to my glucose absorption chain, i.e. stomach -> duodenum -> jenenum -> ileum -> removal, to isolate the cause of this. I had initially thought it may be because I mechanistically model liver glycogen and that does deplete over time, but I've tested enough to show that that does nothing. My next test is to isolate the glucose absorption chain into a seperate model and see if the issue persists but I'm completely baffled!
These are the equations, to my eye there's no reason why there would be such a sharp glucose quantity/time dependence, they all begin at a value of 0:
d(Gs)/dt = -(kw*(1-Gd^14/(Igd^14+Gd^14))*Gs) #Stomach glucose
d(Gd)/dt = (kw*(1-Gd^14/(Igd^14+Gd^14))*Gs) - (kdj*Gd) #Duodenal Glucose
d(Gj)/dt = (kdj*Gd) - (kji*Gj) #Jejunal Glucose
d(Gi)/dt = (kji*Gj) - (kic*Gi) #Ileal Glucose
(The sigmoidicity of gastric emptying slowing term (^14) was parameterised off of paracetamol absorption data and appears to be correct!)
Thank you for your help, best regards,
Dan
Pre-Edit: I changed the run time to 30 hours and now I can't use the 75g input any later than 7.9 hours not 8.5 hours anymore!
Edit: This is how it appears at all times prior to it failing for 75g:
Dear MATLAB contest enthusiasts,
I believe many of you have been captivated by the innovative entries from Zhaoxu Liu / slanderer, in the 2023 MATLAB Flipbook Mini Hack contest.
Ever wondered about the person behind these creative entries? What drives a MATLAB user to such levels of skill? And what inspired his participation in the contest? We were just as curious as you are!
We were delighted to catch up with him and learn more about his use of MATLAB. The interview has recently been published in MathWorks Blogs. For an in-depth look into his insights and experiences, be sure to read our latest blog post: Community Q&A – Zhaoxu Liu.
But the conversation doesn't end here! Who would you like to see featured in our next interview? Drop their name in the comments section below and let us know who we should reach out to next!
Join us for a hands-on workshop focussing on Global Sensitivity Analysis (GSA) for QSP using SimBiology. This complimentary session aims to give you theoretical background and hands-on experience with GSA methods.
🗓️ Event Details: June 25, 1-5pm CEST @PAGE 2024, Rome
🔖 Registration: Free, but space is limited. Early registration is recommended to ensure your place in this workshop.
For more details and to register, please visit https://www.mathworks.com/company/events/seminars/global-sensitivity-analysis-with-simbiology-4361208.html
Hi All,
I'm trying to produce some nice figures from the graphical user interface and have a set of local sensitivity analyses that I'd like to combine.
I have two inputs that vary the sensitivies of my system and would like to plot them on top of each other like:
Is there either a way to do this natively in simbiology (when you try and use 'keep results from each run' it plots them both as a time series) or to export the sensitivity data to the normal matlab programatic UI where I can combine them by hand?
Thank you for your help!
