I am new to simbiology and would appreciate guidance on this issue! I am modeling several reactions inside a cell, which are affecteed by extracellular ligands & membrane bound receptors. Should the plasma membrane be its own compartment in my model? How should I deal with ligand gated receptors in the plasma membrane (I don't have 'concentrations' of those reeceptors in the PM, but do have intracellular mRNA values).
Thanks in advance for everyone's time & help on this.