PKPDmodelNSCLC
Mathematical compartmental formulation of dose-effect synergy modelling for multiple therapies in non small cell lung cancer (NSCLC)
You are now following this Submission
- You will see updates in your followed content feed
- You may receive emails, depending on your communication preferences
A mathematical compartmental formulation of dose-effect synergy modelling for multiple therapies in non small cell lung cancer (NSCLC): antiangiongenic, immuno and radiotherapy. The model formulates the dose-effect relationship in a unified context, with tumor
proliferating rates and necrotic tissue volume progression as a function of therapy management profiles. The model accounts for inter- and intra-response variability by using surface model response terms. Slow acting peripheral compartments such as fat and muscle for drug distribution are not modelled. This minimal pharmacokinetic-pharmacodynamic (PKPD) model is evaluated with reported data in mice from literature.
Cite As
Clara Mihaela Ionescu (2026). PKPDmodelNSCLC (https://nl.mathworks.com/matlabcentral/fileexchange/76838-pkpdmodelnsclc), MATLAB Central File Exchange. Retrieved .
Citation: Clara Mihaela Ionescu *, Maria Ghita, Dana Copot, Eric Derom, Dirk Verellen. A minimal PKPD interaction model for evaluating synergy effects of combined NSCLC therapies, Journal of Clinical Medicine 2020, No. 5; doi:10.3390/jcmxx010005
General Information
- Version 1.0.0 (3.77 KB)
MATLAB Release Compatibility
- Compatible with R2017b to R2020a
Platform Compatibility
- Windows
- macOS
- Linux
| Version | Published | Release Notes | Action |
|---|---|---|---|
| 1.0.0 |
