Why do I receive the error message "Server Creation Failed: Class not registered" when trying to communicate with a COM server using MATLAB?

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When trying to communicate with a third party application using the COM server in MATLAB, I am receiving the following error message,
Server Creation Failed: Class not registered
Why do I receive the error message "Server Creation Failed: Class not registered" when trying to communicate with a COM server using MATLAB?

Accepted Answer

MathWorks Support Team
MathWorks Support Team on 27 Dec 2021
This issue can have two causes:
1.) The DLL that is loaded into MATLAB is a 32-bit DLL but it is used a MATLAB 64-bit version, see the following MATLAB Answers thread for more information,
In such a case the resolution of the issue would involve installing and using a 32-bit version of MATLAB.
2.) The DLL that is loaded in MATLAB through the COM interface does not have the particular class registered.
If the third-party application is run as an out-of-process ActiveX server, then the issue most likely lies in point 2.). To resolve this issue, the developer of the third-party program needs to register the class in the generated DLL, before one can access it through MATLAB via the COM interface.

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R2021b

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